段树燕(博士)

来源:suncitygroup太阳新城 时间:2023-09-28 点击数:

 段树燕,女,博士,讲师。主要研究方向为蛋白结构生物学。2019年1月获复旦大学生物物理专业理学博士学位,2022年11月复旦大学化学生物学专业博后出站,2022年12月入职太阳成集团,主讲《药理学》《计算机设计与基础》《制药工程基础实验》等课程。以第一作者或通讯作者在《International Journal of Biochemistry and Cell Biology》、《Biotechnology Letters》、《ONCOLOGY LETTERS》、《Proceedings of the National Academy of Sciences 》等期刊发表论文多篇;授权发明专利1项;参与科技部国家重点研发计划“蛋白质机器与生命过程调控”重点专项等项目研发。曾获第三届华东结构生物学大会优秀报告奖、全国文学作品二等奖、吉凯生命科学奖学金、药明康德支票奖、复旦大学博士优秀学业奖学金等。

近年来发表的主要代表性论文(“*”通讯作者):

1.Shuyan Duan*, Nan Zhang, Tianzhu Chao, Yaoyao Wu, Mengying Wang* (2023).  The structural and molecular mechanisms of type II PETases: a mini review. Biotechnology letters.

2.Shuyan Duan, Wenqing Gao, Zijun Chen , Zhengyang Li , Suhua Li , Jianhua Gan, Xiangjun Chen, Jixi Li (2020). Crystal structure of human archease, a key cofactor of tRNA splicing ligase complex. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY.

3.Shuyan Duan, Zijun Chen , Zhengyang Li , Rui Ji, Jianhua Gan, Jixi Li(2019). Purification and enzymatic characterization of the RNA ligase RTCB from Thermus thermophilus. Biotechnology letters.

4.Yun Yang, Ziyin Tian , Xinghua Zhao, Ya Li , Shuyan Duan* (2020). A novel antitumor dithiocarbamate compound inhibits the EGFR/AKT signaling pathway and induces apoptosis in esophageal cancer cells. Oncology letters.

5.Kuang S, Zheng J, Yang H, Li S, Duan S, Shen Y, Ji C, Gan J, Xu XW, Li J (2017). Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis. PNAS.

6.段树燕,郭怀祖,李晶,郑娟,赵自叶,张大鹏,王皓(2014)重组 GluV8 的克隆表达、纯化及酶 学性质研究. 中国生物工程杂志.

7.Lei Zhao, Feiyue Xie, Xin Tong, Huafei Li, Yaling Chen, Weizhu Qian , Shuyan Duan, Juan Zheng, Ziye Zhao, Bohua Li, Dapeng Zhang, Jian Zhao, Jianxin Dai, Hao Wang, Sheng Hou, Yajun Guo(2014). Combating non-Hodgkin lymphoma by targeting both CD20 and HLA-DR through CD20-243 CrossMab. MAbs.

8.Lei Zhao, Qin Tong, Weizhu Qian, Bohua Li, Dapeng Zhang, Tuo Fu, Shuyan Duan, Jian Zhao, Jianxin Dai, Hao Wang, Sheng Hou, Yajun Guo(2013).Eradication of non-Hodgkin lymphoma through the induction of tumor-specific T-cell immunity by CD20-Flex BiFP. Blood.

授权发明专利:

1.李继喜,段树燕,纪锐,陈子珺. 人源分子伴侣样蛋白及其表达纯化、晶体结构和应用. 专利号: CN106589104A.



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